Entry Detail


General Information

Database ID:TRD01167
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:AS-tDR-004874
tsRNA Type:i-tRF
Amino acid and Anticodon:LeuTAA;ProAGG;ProCGG;ProTGG
Sequence:TGGTCTAGGGGTATGATTCT
Related Target:N/A
Predicted Target:DGKI//STAB2//NRBP2//AKT2//CAMSAP1//INSR//NKX2-8//PDP2//LRTM2//FAM131B
External Links:
MINTbase ID:tRF-20-9MVKS4I7
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Pro-AGG-2-1
Anticodon:ProAGG
tRNA_number:trna65
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 167684770        End Site(bp): 167684789

[2] gtRNAdb_ID:tRNA-Pro-AGG-2-4
Anticodon:ProAGG
tRNA_number:trna9
Chromosome:11
Strand:+
Coordinate:Start Site(bp): 75946564        End Site(bp): 75946583

[3] gtRNAdb_ID:tRNA-Pro-AGG-2-6
Anticodon:ProAGG
tRNA_number:trna22
Chromosome:14
Strand:-
Coordinate:Start Site(bp): 21081605        End Site(bp): 21081624

[4] gtRNAdb_ID:tRNA-Pro-AGG-2-5
Anticodon:ProAGG
tRNA_number:trna23
Chromosome:14
Strand:-
Coordinate:Start Site(bp): 21077540        End Site(bp): 21077559

[5] gtRNAdb_ID:tRNA-Pro-AGG-2-7
Anticodon:ProAGG
tRNA_number:trna29
Chromosome:16
Strand:-
Coordinate:Start Site(bp): 3232680        End Site(bp): 3232699

[6] gtRNAdb_ID:tRNA-Pro-AGG-2-8
Anticodon:ProAGG
tRNA_number:trna9
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 3239641        End Site(bp): 3239660

[7] gtRNAdb_ID:tRNA-Pro-AGG-2-2
Anticodon:ProAGG
tRNA_number:trna12
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 26555505        End Site(bp): 26555524

[8] gtRNAdb_ID:tRNA-Pro-AGG-2-3
Anticodon:ProAGG
tRNA_number:trna2
Chromosome:7
Strand:+
Coordinate:Start Site(bp): 128423511        End Site(bp): 128423530

[9] gtRNAdb_ID:tRNA-Pro-AGG-1-1
Anticodon:ProAGG
tRNA_number:trna11
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 3241996        End Site(bp): 3242015

[10] gtRNAdb_ID:tRNA-Pro-CGG-2-1
Anticodon:ProCGG
tRNA_number:trna30
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 27059528        End Site(bp): 27059547

[11] gtRNAdb_ID:tRNA-Pro-CGG-1-1
Anticodon:ProCGG
tRNA_number:trna52
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 167683969        End Site(bp): 167683988

[12] gtRNAdb_ID:tRNA-Pro-CGG-1-2
Anticodon:ProCGG
tRNA_number:trna6
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 3222056        End Site(bp): 3222075

[13] gtRNAdb_ID:tRNA-Pro-CGG-1-3
Anticodon:ProCGG
tRNA_number:trna37
Chromosome:17
Strand:-
Coordinate:Start Site(bp): 8126196        End Site(bp): 8126215

[14] gtRNAdb_ID:tRNA-Pro-TGG-3-2
Anticodon:ProTGG
tRNA_number:trna6
Chromosome:14
Strand:+
Coordinate:Start Site(bp): 21152182        End Site(bp): 21152201

[15] gtRNAdb_ID:tRNA-Pro-TGG-3-4
Anticodon:ProTGG
tRNA_number:trna28
Chromosome:16
Strand:-
Coordinate:Start Site(bp): 3234178        End Site(bp): 3234197

[16] gtRNAdb_ID:tRNA-Pro-TGG-3-3
Anticodon:ProTGG
tRNA_number:trna3
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 3208930        End Site(bp): 3208949

[17] gtRNAdb_ID:tRNA-Pro-TGG-3-5
Anticodon:ProTGG
tRNA_number:trna8
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 3238101        End Site(bp): 3238120

[18] gtRNAdb_ID:tRNA-Pro-TGG-3-1
Anticodon:ProTGG
tRNA_number:trna14
Chromosome:5
Strand:-
Coordinate:Start Site(bp): 180615899        End Site(bp): 180615918

[19] gtRNAdb_ID:tRNA-Pro-TGG-2-1
Anticodon:ProTGG
tRNA_number:trna12
Chromosome:11
Strand:-
Coordinate:Start Site(bp): 75946914        End Site(bp): 75946933



tsRNA Association Statistics

Total Associated Disease Number:2
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D051436DOID:784
Disease Name:Renal Insufficiency, Chronicchronic kidney disease
Category:MeSHDisease Ontology
Type:Urogenital Diseases//Pathological Conditions, Signs and Symptomsdisease of anatomical entity
Define:Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)A kidney failure that is characterized by the gradual loss of kidney function.
Alias:Chronic Kidney Diseases//Chronic Kidney Insufficiency//Chronic Renal Diseases//Chronic Renal Insufficiency//Kidney Insufficiency, ChronicN/A



Disease Association Statistics

Total Associated tsRNA Number:197
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:31629473
Disease Name:Renal Insufficiency, Chronic
Tissue:Kidney
Dysfunction Pattern:Down-Regulation
Validated Method:High-throughput sequencing
Description:In this study, 147 differentially expressed (fold change > 2, P < 0.05) tRFs were identified. Specifically, 69 tRFs were up-regulated and 70 tRFs were down-regulated.
Comparision:Differentiated Podocytes VS Undifferentiated Podocytes
Mechanism:N/A