Entry Detail


General Information

Database ID:TRD00954
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:AS-tDR-008258
tsRNA Type:i-tRF
Amino acid and Anticodon:GlyGCC
Sequence:TGGTTCAGTGGTAGAAT
Related Target:N/A
Predicted Target:FCGR2A//STAMBPL1//PCGF5//LRRC15//USP31//POLR1A//MUC16//CSN3//SLC12A7//SPRN
External Links:
MINTbase ID:tRF-17-9NJ4S2I
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Gly-CCC-6-1
Anticodon:GlyCCC
tRNA_number:trna91
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 149680257        End Site(bp): 149680273

[2] gtRNAdb_ID:tRNA-Glu-TTC-9-1
Anticodon:GluTTC
tRNA_number:trna17
Chromosome:2
Strand:-
Coordinate:Start Site(bp): 204229178        End Site(bp): 204229194

[3] gtRNAdb_ID:tRNA-Gly-CCC-1-1
Anticodon:GlyCCC
tRNA_number:trna133
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 16872481        End Site(bp): 16872497

[4] gtRNAdb_ID:tRNA-Gly-CCC-1-2
Anticodon:GlyCCC
tRNA_number:trna4
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 17188423        End Site(bp): 17188439

[5] gtRNAdb_ID:tRNA-Gly-GCC-5-1
Anticodon:GlyGCC
tRNA_number:trna18
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 70822604        End Site(bp): 70822620

[6] gtRNAdb_ID:tRNA-Gly-GCC-4-1
Anticodon:GlyGCC
tRNA_number:trna43
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 161450363        End Site(bp): 161450379

[7] gtRNAdb_ID:tRNA-Gly-GCC-3-1
Anticodon:GlyGCC
tRNA_number:trna25
Chromosome:16
Strand:-
Coordinate:Start Site(bp): 70812161        End Site(bp): 70812177

[8] gtRNAdb_ID:tRNA-Gly-GCC-2-1
Anticodon:GlyGCC
tRNA_number:trna68
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 161493684        End Site(bp): 161493700

[9] gtRNAdb_ID:tRNA-Gly-GCC-2-5
Anticodon:GlyGCC
tRNA_number:trna19
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 70823417        End Site(bp): 70823433

[10] gtRNAdb_ID:tRNA-Gly-GCC-2-4
Anticodon:GlyGCC
tRNA_number:trna24
Chromosome:16
Strand:-
Coordinate:Start Site(bp): 70812989        End Site(bp): 70813005

[11] gtRNAdb_ID:tRNA-Gly-GCC-2-6
Anticodon:GlyGCC
tRNA_number:trna5
Chromosome:17
Strand:+
Coordinate:Start Site(bp): 8029071        End Site(bp): 8029087

[12] gtRNAdb_ID:tRNA-Gly-GCC-2-2
Anticodon:GlyGCC
tRNA_number:trna19
Chromosome:2
Strand:-
Coordinate:Start Site(bp): 157257706        End Site(bp): 157257722

[13] gtRNAdb_ID:tRNA-Gly-GCC-2-3
Anticodon:GlyGCC
tRNA_number:trna128
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27870733        End Site(bp): 27870749

[14] gtRNAdb_ID:tRNA-Gly-GCC-1-1
Anticodon:GlyGCC
tRNA_number:trna35
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 161413101        End Site(bp): 161413117

[15] gtRNAdb_ID:tRNA-Gly-GCC-1-2
Anticodon:GlyGCC
tRNA_number:trna37
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 161420474        End Site(bp): 161420490

[16] gtRNAdb_ID:tRNA-Gly-GCC-1-3
Anticodon:GlyGCC
tRNA_number:trna39
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 161427905        End Site(bp): 161427921

[17] gtRNAdb_ID:tRNA-Gly-GCC-1-4
Anticodon:GlyGCC
tRNA_number:trna41
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 161435265        End Site(bp): 161435281

[18] gtRNAdb_ID:tRNA-Gly-GCC-1-5
Anticodon:GlyGCC
tRNA_number:trna2
Chromosome:21
Strand:-
Coordinate:Start Site(bp): 18827154        End Site(bp): 18827170

[19] gtRNAdb_ID:tRNA-Val-CAC-8-1
Anticodon:ValCAC
tRNA_number:trna99
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 149294713        End Site(bp): 149294729



tsRNA Association Statistics

Total Associated Disease Number:2
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D051436DOID:784
Disease Name:Renal Insufficiency, Chronicchronic kidney disease
Category:MeSHDisease Ontology
Type:Urogenital Diseases//Pathological Conditions, Signs and Symptomsdisease of anatomical entity
Define:Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)A kidney failure that is characterized by the gradual loss of kidney function.
Alias:Chronic Kidney Diseases//Chronic Kidney Insufficiency//Chronic Renal Diseases//Chronic Renal Insufficiency//Kidney Insufficiency, ChronicN/A



Disease Association Statistics

Total Associated tsRNA Number:197
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:31629473
Disease Name:Renal Insufficiency, Chronic
Tissue:Kidney
Dysfunction Pattern:Down-Regulation
Validated Method:High-throughput sequencing
Description:In this study, 147 differentially expressed (fold change > 2, P < 0.05) tRFs were identified. Specifically, 69 tRFs were up-regulated and 70 tRFs were down-regulated.
Comparision:Differentiated Podocytes VS Undifferentiated Podocytes
Mechanism:N/A