Entry Detail


General Information

Database ID:TRD00935
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-16-9NJ4S2B
tsRNA Type:i-tRF
Amino acid and Anticodon:GlyCCC;GluTTC;GlyGCC;ValCAC
Sequence:TGGTTCAGTGGTAGAA
Related Target:N/A
Predicted Target:FCGR2A//MUC16//STAMBPL1//CSN3//LRRC15//PCGF5//PSCA//NCAN//USP31//POLR1A
External Links:
MINTbase ID:tRF-16-9NJ4S2B
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Gly-CCC-6-1
Anticodon:GlyCCC
tRNA_number:trna91
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 149680258        End Site(bp): 149680273

[2] gtRNAdb_ID:tRNA-Glu-TTC-9-1
Anticodon:GluTTC
tRNA_number:trna17
Chromosome:2
Strand:-
Coordinate:Start Site(bp): 204229179        End Site(bp): 204229194

[3] gtRNAdb_ID:tRNA-Gly-CCC-1-1
Anticodon:GlyCCC
tRNA_number:trna133
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 16872482        End Site(bp): 16872497

[4] gtRNAdb_ID:tRNA-Gly-CCC-1-2
Anticodon:GlyCCC
tRNA_number:trna4
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 17188423        End Site(bp): 17188438

[5] gtRNAdb_ID:tRNA-Gly-GCC-5-1
Anticodon:GlyGCC
tRNA_number:trna18
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 70822604        End Site(bp): 70822619

[6] gtRNAdb_ID:tRNA-Gly-GCC-4-1
Anticodon:GlyGCC
tRNA_number:trna43
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 161450363        End Site(bp): 161450378

[7] gtRNAdb_ID:tRNA-Gly-GCC-3-1
Anticodon:GlyGCC
tRNA_number:trna25
Chromosome:16
Strand:-
Coordinate:Start Site(bp): 70812162        End Site(bp): 70812177

[8] gtRNAdb_ID:tRNA-Gly-GCC-2-1
Anticodon:GlyGCC
tRNA_number:trna68
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 161493685        End Site(bp): 161493700

[9] gtRNAdb_ID:tRNA-Gly-GCC-2-5
Anticodon:GlyGCC
tRNA_number:trna19
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 70823417        End Site(bp): 70823432

[10] gtRNAdb_ID:tRNA-Gly-GCC-2-4
Anticodon:GlyGCC
tRNA_number:trna24
Chromosome:16
Strand:-
Coordinate:Start Site(bp): 70812990        End Site(bp): 70813005

[11] gtRNAdb_ID:tRNA-Gly-GCC-2-6
Anticodon:GlyGCC
tRNA_number:trna5
Chromosome:17
Strand:+
Coordinate:Start Site(bp): 8029071        End Site(bp): 8029086

[12] gtRNAdb_ID:tRNA-Gly-GCC-2-2
Anticodon:GlyGCC
tRNA_number:trna19
Chromosome:2
Strand:-
Coordinate:Start Site(bp): 157257707        End Site(bp): 157257722

[13] gtRNAdb_ID:tRNA-Gly-GCC-2-3
Anticodon:GlyGCC
tRNA_number:trna128
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27870734        End Site(bp): 27870749

[14] gtRNAdb_ID:tRNA-Gly-GCC-1-1
Anticodon:GlyGCC
tRNA_number:trna35
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 161413101        End Site(bp): 161413116

[15] gtRNAdb_ID:tRNA-Gly-GCC-1-2
Anticodon:GlyGCC
tRNA_number:trna37
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 161420474        End Site(bp): 161420489

[16] gtRNAdb_ID:tRNA-Gly-GCC-1-3
Anticodon:GlyGCC
tRNA_number:trna39
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 161427905        End Site(bp): 161427920

[17] gtRNAdb_ID:tRNA-Gly-GCC-1-4
Anticodon:GlyGCC
tRNA_number:trna41
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 161435265        End Site(bp): 161435280

[18] gtRNAdb_ID:tRNA-Gly-GCC-1-5
Anticodon:GlyGCC
tRNA_number:trna2
Chromosome:21
Strand:-
Coordinate:Start Site(bp): 18827155        End Site(bp): 18827170

[19] gtRNAdb_ID:tRNA-Val-CAC-8-1
Anticodon:ValCAC
tRNA_number:trna99
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 149294714        End Site(bp): 149294729



tsRNA Association Statistics

Total Associated Disease Number:1
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D015451DOID:1040
Disease Name:Leukemia, Lymphocytic, Chronic, B-Cellchronic lymphocytic leukemia
Category:MeSHDisease Ontology
Type:Neoplasms//Hemic and Lymphatic Diseases//Immune System Diseases//Pathological Conditions, Signs and Symptomsdisease of anatomical entity//disease of cellular proliferation
Define:A chronic leukemia characterized by abnormal B-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and bone marrow involvement it is called chronic lymphocytic leukemia (CLL); in those predominately with enlarged lymph nodes it is called small lymphocytic lymphoma. These terms represent spectrums of the same disease.A lymphocytic leukemia characterized by over production of B-cells and their accumulation in bone marrow and blood.
Alias:B-Cell Chronic Lymphocytic Leukemia//B-Cell Leukemia, Chronic//B-Cell Malignancy, Low-Grade//B-Lymphocytic Leukemia, Chronic//Chronic Lymphocytic Leukemia//Diffuse Well-Differentiated Lymphocytic Lymphoma//Disrupted In B-Cell Malignancy//Leukemia, B Cell, Chronic//Leukemia, B-Cell, Chronic//Leukemia, Chronic Lymphatic//Leukemia, Chronic Lymphocytic//Leukemia, Chronic Lymphocytic, B-Cell//Leukemia, Lymphoblastic, Chronic//Leukemia, Lymphocytic, Chronic//Leukemia, Lymphocytic, Chronic, B Cell//Lymphoblastic Leukemia, Chronic//Lymphocytic Leukemia, Chronic//Lymphocytic Leukemia, Chronic, B Cell//Lymphocytic Leukemia, Chronic, B-Cell//Lymphocytic Lymphoma//Lymphocytic Lymphoma, Diffuse, Well Differentiated//Lymphocytic Lymphoma, Diffuse, Well-Differentiated//Lymphocytic Lymphoma, Well Differentiated//Lymphocytic Lymphoma, Well-Differentiated//Lymphoma, Lymphocytic//Lymphoma, Lymphocytic, Diffuse, Well Differentiated//Lymphoma, Lymphocytic, Diffuse, Well-Differentiated//Lymphoma, Lymphocytic, Well Differentiated//Lymphoma, Lymphocytic, Well-Differentiated//Lymphoma, Lymphoplasmacytoid, CLL//Lymphoma, Small Lymphocytic//Lymphoma, Small Lymphocytic, Plasmacytoid//Lymphoma, Small-Cell//Lymphoplasmacytoid Lymphoma, CLL//Small-Cell LymphomaB-cell chronic lymphocytic leukaemia//B-cell chronic lymphocytic leukemia//B-cell chronic lymphoid leukemia//chronic lymphatic leukaemia//chronic lymphatic leukemia//chronic lymphocytic leukaemia//CLL//lymphoplasmacytic leukaemia//lymphoplasmacytic leukemia



Disease Association Statistics

Total Associated tsRNA Number:1731
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:31723042
Disease Name:Leukemia, Lymphocytic, Chronic, B-Cell
Tissue:Chronic Lymphocytic Leukemia
Dysfunction Pattern:Up-Regulation
Validated Method:High-throughput sequencing
Description:We identified tsRNA signatures in aggressive and indolent CLL. We further analyzed the expression of mature tRFs and found that mature tRFs are drastically dysregulated in CLL.
Comparision:Cancer VS Normal
Mechanism:N/A