Entry Detail


General Information

Database ID:TRD00862
Confidence:High
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-21-SWRYVMMV0
tsRNA Type:i-tRF
Amino acid and Anticodon:GluTTC
Sequence:GTCGTGGTTGTAGTCCGTGCG
Related Target:N/A
Predicted Target:CACNG8//C5AR1//MMP2//IRF2BP1//FAM184A//ZNF688//FZD8//TCP1//B4GALT7//SYNGR1
External Links:
MINTbase ID:tRF-21-SWRYVMMV0
tRFdb ID:N/A

[1] gtRNAdb_ID:-
Anticodon:GluTTC
tRNA_number:trnaMT
Chromosome:MT
Strand:-
Coordinate:Start Site(bp): 14680        End Site(bp): 14700

[2] gtRNAdb_ID:-
Anticodon:GluTTC
tRNA_number:trnalookalike8
Chromosome:5
Strand:-
Coordinate:Start Site(bp): 93905178        End Site(bp): 93905198



tsRNA Association Statistics

Total Associated Disease Number:5
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D006332N/A
Disease Name:CardiomegalyN/A
Category:MeSHDisease Ontology
Type:Cardiovascular Diseases//Pathological Conditions, Signs and SymptomsN/A
Define:Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.N/A
Alias:Cardiac Hypertrophy//Enlarged Heart//Heart Enlargement//Heart HypertrophyN/A



Disease Association Statistics

Total Associated tsRNA Number:68
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:RT-PCR
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:37370960
Disease Name:Cardiomegaly
Tissue:Plasma
Dysfunction Pattern:Down-Regulation
Validated Method:RT-PCR//High-throughput sequencing
Description:As shown in Figure 3A, the expression levels of tRF-30-3JVIJMRPFQ5D, tRF-16-R29P4PE, tRF-21-NB8PLML3E, and tRF-21-SWRYVMMV0 were significantly downregulated (p < 0.05 or p < 0.01).
Comparision:Disease VS Control
Mechanism:N/A