Entry Detail


General Information

Database ID:TRD00637
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:AS-tDR-002315
tsRNA Type:i-tRF
Amino acid and Anticodon:GlnCTG;GlnTTG
Sequence:ATGGTTAGCACTCTGG
Related Target:N/A
Predicted Target:MUC5B//NEFL//LRP1B//DRICH1//PKD1//ASPG//NRG1//CDCA7L//LARGE2//MGAT4A
External Links:
MINTbase ID:tRF-16-I3VF4Y0
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Gln-CTG-5-1
Anticodon:GlnCTG
tRNA_number:trna42
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 27263226        End Site(bp): 27263241

[2] gtRNAdb_ID:tRNA-Gln-CTG-2-1
Anticodon:GlnCTG
tRNA_number:trna146
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27515573        End Site(bp): 27515588

[3] gtRNAdb_ID:tRNA-Gln-CTG-1-4
Anticodon:GlnCTG
tRNA_number:trna7
Chromosome:15
Strand:-
Coordinate:Start Site(bp): 66161442        End Site(bp): 66161457

[4] gtRNAdb_ID:tRNA-Gln-CTG-1-5
Anticodon:GlnCTG
tRNA_number:trna3
Chromosome:17
Strand:+
Coordinate:Start Site(bp): 8023084        End Site(bp): 8023099

[5] gtRNAdb_ID:tRNA-Gln-CTG-1-1
Anticodon:GlnCTG
tRNA_number:trna1
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 18836416        End Site(bp): 18836431

[6] gtRNAdb_ID:tRNA-Gln-CTG-1-2
Anticodon:GlnCTG
tRNA_number:trna49
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 27487322        End Site(bp): 27487337

[7] gtRNAdb_ID:tRNA-Gln-CTG-1-3
Anticodon:GlnCTG
tRNA_number:trna99
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 28909420        End Site(bp): 28909435

[8] gtRNAdb_ID:tRNA-Gln-TTG-4-1
Anticodon:GlnTTG
tRNA_number:trna84
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 145503873        End Site(bp): 145503888

[9] gtRNAdb_ID:tRNA-Gln-TTG-3-3
Anticodon:GlnTTG
tRNA_number:trna130
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27763682        End Site(bp): 27763697

[10] gtRNAdb_ID:tRNA-Gln-TTG-3-2
Anticodon:GlnTTG
tRNA_number:trna173
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 26312017        End Site(bp): 26312032

[11] gtRNAdb_ID:tRNA-Gln-TTG-3-1
Anticodon:GlnTTG
tRNA_number:trna174
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 26311466        End Site(bp): 26311481

[12] gtRNAdb_ID:tRNA-Gln-TTG-2-1
Anticodon:GlnTTG
tRNA_number:trna64
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 28557170        End Site(bp): 28557185

[13] gtRNAdb_ID:tRNA-Gln-TTG-1-1
Anticodon:GlnTTG
tRNA_number:trna16
Chromosome:17
Strand:+
Coordinate:Start Site(bp): 47269904        End Site(bp): 47269919



tsRNA Association Statistics

Total Associated Disease Number:2
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D051436DOID:784
Disease Name:Renal Insufficiency, Chronicchronic kidney disease
Category:MeSHDisease Ontology
Type:Urogenital Diseases//Pathological Conditions, Signs and Symptomsdisease of anatomical entity
Define:Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)A kidney failure that is characterized by the gradual loss of kidney function.
Alias:Chronic Kidney Diseases//Chronic Kidney Insufficiency//Chronic Renal Diseases//Chronic Renal Insufficiency//Kidney Insufficiency, ChronicN/A



Disease Association Statistics

Total Associated tsRNA Number:197
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:31629473
Disease Name:Renal Insufficiency, Chronic
Tissue:Kidney
Dysfunction Pattern:Up-Regulation
Validated Method:High-throughput sequencing
Description:In this study, 147 differentially expressed (fold change > 2, P < 0.05) tRFs were identified. Specifically, 69 tRFs were up-regulated and 70 tRFs were down-regulated.
Comparision:Differentiated Podocytes VS Undifferentiated Podocytes
Mechanism:N/A