Entry Detail



General Information

Database ID:TRD00635
Confidence:High
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRFi-GlnCTG
tsRNA Type:i-tRF
Amino acid and Anticodon:GlnCTG
Sequence:N/A
Related Target:N/A
Predicted Target:N/A
External Links:
MINTbase ID:N/A
tRFdb ID:N/A



tsRNA Association Statistics

Total Associated Disease Number:4
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D020212DOID:3407
Disease Name:Carotid Artery Injuriescarotid artery disease
Category:MeSHDisease Ontology
Type:Nervous System Diseases//Cardiovascular Diseases//Wounds and Injuriesdisease of anatomical entity
Define:Damages to the CAROTID ARTERIES caused either by blunt force or penetrating trauma, such as CRANIOCEREBRAL TRAUMA; THORACIC INJURIES; and NECK INJURIES. Damaged carotid arteries can lead to CAROTID ARTERY THROMBOSIS; CAROTID-CAVERNOUS SINUS FISTULA; pseudoaneurysm formation; and INTERNAL CAROTID ARTERY DISSECTION. (From Am J Forensic Med Pathol 1997, 18:251; J Trauma 1994, 37:473)N/A
Alias:Carotid Arteriopathies, Traumatic//Carotid False Aneurysm//Carotid Pseudoaneurysm//False Aneurysm, Carotid//Injuries, Carotid Artery//Trauma, Carotid Arterydisorder of carotid artery



Disease Association Statistics

Total Associated tsRNA Number:47
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:RT-PCR
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:33552681
Disease Name:Carotid Artery Injuries
Tissue:The Normal And The Balloon-Injured Rat CCAs
Dysfunction Pattern:Up-Regulation
Validated Method:RT-PCR//High-throughput sequencing
Description:tRNA-derived fragments tRFGlnCTG induced by arterial injury promote vascular smooth muscle cell proliferation.
Comparision:Normal VS the Balloon-Injured Rat CCAs
Mechanism:The investigation of the roles of tRFs/ tiRNAs is of significance for understanding the mechanism, diagnosis, and treatment of intimal hyperplasia.