Entry Detail


General Information

Database ID:TRD00621
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-16-299DWUB
tsRNA Type:i-tRF
Amino acid and Anticodon:GlnCTG
Sequence:CACTCTGGACTCTGAA
Related Target:N/A
Predicted Target:RAD54L//LCAT//ZNF518A//MYOM3//PTCD1//DCX//NEFL//TOR4A//TMEM178B//EXD3
External Links:
MINTbase ID:tRF-16-299DWUB
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Gln-CTG-7-1
Anticodon:GlnCTG
tRNA_number:trna22
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 147800959        End Site(bp): 147800974

[2] gtRNAdb_ID:tRNA-Gln-CTG-6-1
Anticodon:GlnCTG
tRNA_number:trna131
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27759169        End Site(bp): 27759184

[3] gtRNAdb_ID:tRNA-Gln-CTG-5-1
Anticodon:GlnCTG
tRNA_number:trna42
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 27263234        End Site(bp): 27263249

[4] gtRNAdb_ID:tRNA-Gln-CTG-4-1
Anticodon:GlnCTG
tRNA_number:trna112
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 147737416        End Site(bp): 147737431

[5] gtRNAdb_ID:tRNA-Gln-CTG-4-2
Anticodon:GlnCTG
tRNA_number:trna28
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 149186147        End Site(bp): 149186162

[6] gtRNAdb_ID:tRNA-Gln-CTG-3-1
Anticodon:GlnCTG
tRNA_number:trna15
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 145963326        End Site(bp): 145963341

[7] gtRNAdb_ID:tRNA-Gln-CTG-3-2
Anticodon:GlnCTG
tRNA_number:trna19
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 147505060        End Site(bp): 147505075

[8] gtRNAdb_ID:tRNA-Gln-CTG-2-1
Anticodon:GlnCTG
tRNA_number:trna146
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27515565        End Site(bp): 27515580

[9] gtRNAdb_ID:tRNA-Gln-CTG-1-4
Anticodon:GlnCTG
tRNA_number:trna7
Chromosome:15
Strand:-
Coordinate:Start Site(bp): 66161434        End Site(bp): 66161449

[10] gtRNAdb_ID:tRNA-Gln-CTG-1-5
Anticodon:GlnCTG
tRNA_number:trna3
Chromosome:17
Strand:+
Coordinate:Start Site(bp): 8023092        End Site(bp): 8023107

[11] gtRNAdb_ID:tRNA-Gln-CTG-1-1
Anticodon:GlnCTG
tRNA_number:trna1
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 18836424        End Site(bp): 18836439

[12] gtRNAdb_ID:tRNA-Gln-CTG-1-2
Anticodon:GlnCTG
tRNA_number:trna49
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 27487330        End Site(bp): 27487345

[13] gtRNAdb_ID:tRNA-Gln-CTG-1-3
Anticodon:GlnCTG
tRNA_number:trna99
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 28909412        End Site(bp): 28909427



tsRNA Association Statistics

Total Associated Disease Number:1
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D015451DOID:1040
Disease Name:Leukemia, Lymphocytic, Chronic, B-Cellchronic lymphocytic leukemia
Category:MeSHDisease Ontology
Type:Neoplasms//Hemic and Lymphatic Diseases//Immune System Diseases//Pathological Conditions, Signs and Symptomsdisease of anatomical entity//disease of cellular proliferation
Define:A chronic leukemia characterized by abnormal B-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and bone marrow involvement it is called chronic lymphocytic leukemia (CLL); in those predominately with enlarged lymph nodes it is called small lymphocytic lymphoma. These terms represent spectrums of the same disease.A lymphocytic leukemia characterized by over production of B-cells and their accumulation in bone marrow and blood.
Alias:B-Cell Chronic Lymphocytic Leukemia//B-Cell Leukemia, Chronic//B-Cell Malignancy, Low-Grade//B-Lymphocytic Leukemia, Chronic//Chronic Lymphocytic Leukemia//Diffuse Well-Differentiated Lymphocytic Lymphoma//Disrupted In B-Cell Malignancy//Leukemia, B Cell, Chronic//Leukemia, B-Cell, Chronic//Leukemia, Chronic Lymphatic//Leukemia, Chronic Lymphocytic//Leukemia, Chronic Lymphocytic, B-Cell//Leukemia, Lymphoblastic, Chronic//Leukemia, Lymphocytic, Chronic//Leukemia, Lymphocytic, Chronic, B Cell//Lymphoblastic Leukemia, Chronic//Lymphocytic Leukemia, Chronic//Lymphocytic Leukemia, Chronic, B Cell//Lymphocytic Leukemia, Chronic, B-Cell//Lymphocytic Lymphoma//Lymphocytic Lymphoma, Diffuse, Well Differentiated//Lymphocytic Lymphoma, Diffuse, Well-Differentiated//Lymphocytic Lymphoma, Well Differentiated//Lymphocytic Lymphoma, Well-Differentiated//Lymphoma, Lymphocytic//Lymphoma, Lymphocytic, Diffuse, Well Differentiated//Lymphoma, Lymphocytic, Diffuse, Well-Differentiated//Lymphoma, Lymphocytic, Well Differentiated//Lymphoma, Lymphocytic, Well-Differentiated//Lymphoma, Lymphoplasmacytoid, CLL//Lymphoma, Small Lymphocytic//Lymphoma, Small Lymphocytic, Plasmacytoid//Lymphoma, Small-Cell//Lymphoplasmacytoid Lymphoma, CLL//Small-Cell LymphomaB-cell chronic lymphocytic leukaemia//B-cell chronic lymphocytic leukemia//B-cell chronic lymphoid leukemia//chronic lymphatic leukaemia//chronic lymphatic leukemia//chronic lymphocytic leukaemia//CLL//lymphoplasmacytic leukaemia//lymphoplasmacytic leukemia



Disease Association Statistics

Total Associated tsRNA Number:1731
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:31723042
Disease Name:Leukemia, Lymphocytic, Chronic, B-Cell
Tissue:Chronic Lymphocytic Leukemia
Dysfunction Pattern:Down-Regulation
Validated Method:High-throughput sequencing
Description:We identified tsRNA signatures in aggressive and indolent CLL. We further analyzed the expression of mature tRFs and found that mature tRFs are drastically dysregulated in CLL.
Comparision:Cancer VS Normal
Mechanism:N/A