Entry Detail


General Information

Database ID:TRD00543
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-31-QKF1R3WE8RO80
tsRNA Type:i-tRF
Amino acid and Anticodon:AspGTC
Sequence:GCGGGAGACCGGGGTTCGATTCCCCGACGGG
Related Target:N/A
Predicted Target:FBXL14//LRRC37B//SYNJ2//TMEM59L//INPP5E//EGLN2//CNOT8//RAB3B//SH3D21//FAM47B
External Links:
MINTbase ID:tRF-31-QKF1R3WE8RO80
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Asp-GTC-3-1
Anticodon:AspGTC
tRNA_number:trna144
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27551239        End Site(bp): 27551269

[2] gtRNAdb_ID:tRNA-Asp-GTC-2-5
Anticodon:AspGTC
tRNA_number:trna69
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 161440208        End Site(bp): 161440238

[3] gtRNAdb_ID:tRNA-Asp-GTC-2-4
Anticodon:AspGTC
tRNA_number:trna72
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 161432827        End Site(bp): 161432857

[4] gtRNAdb_ID:tRNA-Asp-GTC-2-3
Anticodon:AspGTC
tRNA_number:trna75
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 161425417        End Site(bp): 161425447

[5] gtRNAdb_ID:tRNA-Asp-GTC-2-2
Anticodon:AspGTC
tRNA_number:trna78
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 161418036        End Site(bp): 161418066

[6] gtRNAdb_ID:tRNA-Asp-GTC-2-1
Anticodon:AspGTC
tRNA_number:trna81
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 161410618        End Site(bp): 161410648

[7] gtRNAdb_ID:tRNA-Asp-GTC-2-10
Anticodon:AspGTC
tRNA_number:trna10
Chromosome:12
Strand:-
Coordinate:Start Site(bp): 125424196        End Site(bp): 125424226

[8] gtRNAdb_ID:tRNA-Asp-GTC-2-9
Anticodon:AspGTC
tRNA_number:trna12
Chromosome:12
Strand:-
Coordinate:Start Site(bp): 125411894        End Site(bp): 125411924

[9] gtRNAdb_ID:tRNA-Asp-GTC-2-8
Anticodon:AspGTC
tRNA_number:trna4
Chromosome:12
Strand:+
Coordinate:Start Site(bp): 96429837        End Site(bp): 96429867

[10] gtRNAdb_ID:tRNA-Asp-GTC-2-11
Anticodon:AspGTC
tRNA_number:trna38
Chromosome:17
Strand:-
Coordinate:Start Site(bp): 8125559        End Site(bp): 8125589

[11] gtRNAdb_ID:tRNA-Asp-GTC-2-6
Anticodon:AspGTC
tRNA_number:trna45
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 27447491        End Site(bp): 27447521

[12] gtRNAdb_ID:tRNA-Asp-GTC-2-7
Anticodon:AspGTC
tRNA_number:trna48
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 27471561        End Site(bp): 27471591



tsRNA Association Statistics

Total Associated Disease Number:3
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D015451DOID:1040
Disease Name:Leukemia, Lymphocytic, Chronic, B-Cellchronic lymphocytic leukemia
Category:MeSHDisease Ontology
Type:Neoplasms//Hemic and Lymphatic Diseases//Immune System Diseases//Pathological Conditions, Signs and Symptomsdisease of anatomical entity//disease of cellular proliferation
Define:A chronic leukemia characterized by abnormal B-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and bone marrow involvement it is called chronic lymphocytic leukemia (CLL); in those predominately with enlarged lymph nodes it is called small lymphocytic lymphoma. These terms represent spectrums of the same disease.A lymphocytic leukemia characterized by over production of B-cells and their accumulation in bone marrow and blood.
Alias:B-Cell Chronic Lymphocytic Leukemia//B-Cell Leukemia, Chronic//B-Cell Malignancy, Low-Grade//B-Lymphocytic Leukemia, Chronic//Chronic Lymphocytic Leukemia//Diffuse Well-Differentiated Lymphocytic Lymphoma//Disrupted In B-Cell Malignancy//Leukemia, B Cell, Chronic//Leukemia, B-Cell, Chronic//Leukemia, Chronic Lymphatic//Leukemia, Chronic Lymphocytic//Leukemia, Chronic Lymphocytic, B-Cell//Leukemia, Lymphoblastic, Chronic//Leukemia, Lymphocytic, Chronic//Leukemia, Lymphocytic, Chronic, B Cell//Lymphoblastic Leukemia, Chronic//Lymphocytic Leukemia, Chronic//Lymphocytic Leukemia, Chronic, B Cell//Lymphocytic Leukemia, Chronic, B-Cell//Lymphocytic Lymphoma//Lymphocytic Lymphoma, Diffuse, Well Differentiated//Lymphocytic Lymphoma, Diffuse, Well-Differentiated//Lymphocytic Lymphoma, Well Differentiated//Lymphocytic Lymphoma, Well-Differentiated//Lymphoma, Lymphocytic//Lymphoma, Lymphocytic, Diffuse, Well Differentiated//Lymphoma, Lymphocytic, Diffuse, Well-Differentiated//Lymphoma, Lymphocytic, Well Differentiated//Lymphoma, Lymphocytic, Well-Differentiated//Lymphoma, Lymphoplasmacytoid, CLL//Lymphoma, Small Lymphocytic//Lymphoma, Small Lymphocytic, Plasmacytoid//Lymphoma, Small-Cell//Lymphoplasmacytoid Lymphoma, CLL//Small-Cell LymphomaB-cell chronic lymphocytic leukaemia//B-cell chronic lymphocytic leukemia//B-cell chronic lymphoid leukemia//chronic lymphatic leukaemia//chronic lymphatic leukemia//chronic lymphocytic leukaemia//CLL//lymphoplasmacytic leukaemia//lymphoplasmacytic leukemia



Disease Association Statistics

Total Associated tsRNA Number:1731
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:31723042
Disease Name:Leukemia, Lymphocytic, Chronic, B-Cell
Tissue:Chronic Lymphocytic Leukemia
Dysfunction Pattern:Down-Regulation
Validated Method:High-throughput sequencing
Description:We identified tsRNA signatures in aggressive and indolent CLL. We further analyzed the expression of mature tRFs and found that mature tRFs are drastically dysregulated in CLL.
Comparision:Cancer VS Normal
Mechanism:N/A