Entry Detail



General Information

Database ID:TRD00451
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:AS-tDR-001757
tsRNA Type:i-tRF
Amino acid and Anticodon:AsnGTT
Sequence:TCGGCTGTTAACCGAAAGGTTGGTGGT
Related Target:N/A
Predicted Target:PI4KB//SKOR2//PTPRD//PDE4DIP//JAG1//IFIT3//KPNA6//ESPN//CACNG8//TRPM7
External Links:
MINTbase ID:tRF-27-WJ9X0UD394N
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Asn-GTT-6-1
Anticodon:AsnGTT
tRNA_number:trna103
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 149230589        End Site(bp): 149230615

[2] gtRNAdb_ID:tRNA-Asn-GTT-3-2
Anticodon:AsnGTT
tRNA_number:trna107
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 148760375        End Site(bp): 148760401

[3] gtRNAdb_ID:tRNA-Asn-GTT-3-1
Anticodon:AsnGTT
tRNA_number:trna108
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 148598333        End Site(bp): 148598359

[4] gtRNAdb_ID:tRNA-Asn-GTT-2-1
Anticodon:AsnGTT
tRNA_number:trna26
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 148248143        End Site(bp): 148248169

[5] gtRNAdb_ID:tRNA-Asn-GTT-2-2
Anticodon:AsnGTT
tRNA_number:trna83
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 161397886        End Site(bp): 161397912

[6] gtRNAdb_ID:tRNA-Asn-GTT-2-3
Anticodon:AsnGTT
tRNA_number:trna4
Chromosome:10
Strand:-
Coordinate:Start Site(bp): 22518457        End Site(bp): 22518483

[7] gtRNAdb_ID:tRNA-Asn-GTT-2-4
Anticodon:AsnGTT
tRNA_number:trna7
Chromosome:13
Strand:-
Coordinate:Start Site(bp): 31248120        End Site(bp): 31248146

[8] gtRNAdb_ID:tRNA-Asn-GTT-2-5
Anticodon:AsnGTT
tRNA_number:trna31
Chromosome:17
Strand:-
Coordinate:Start Site(bp): 36908053        End Site(bp): 36908079

[9] gtRNAdb_ID:tRNA-Asn-GTT-2-6
Anticodon:AsnGTT
tRNA_number:trna1
Chromosome:19
Strand:+
Coordinate:Start Site(bp): 1383590        End Site(bp): 1383616

[10] gtRNAdb_ID:tRNA-Asn-GTT-1-1
Anticodon:AsnGTT
tRNA_number:trna47
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 161510059        End Site(bp): 161510085



tsRNA Association Statistics

Total Associated Disease Number:2
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D051436DOID:784
Disease Name:Renal Insufficiency, Chronicchronic kidney disease
Category:MeSHDisease Ontology
Type:Urogenital Diseases//Pathological Conditions, Signs and Symptomsdisease of anatomical entity
Define:Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)A kidney failure that is characterized by the gradual loss of kidney function.
Alias:Chronic Kidney Diseases//Chronic Kidney Insufficiency//Chronic Renal Diseases//Chronic Renal Insufficiency//Kidney Insufficiency, ChronicN/A



Disease Association Statistics

Total Associated tsRNA Number:197
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:31629473
Disease Name:Renal Insufficiency, Chronic
Tissue:Kidney
Dysfunction Pattern:Up-Regulation
Validated Method:High-throughput sequencing
Description:In this study, 147 differentially expressed (fold change > 2, P < 0.05) tRFs were identified. Specifically, 69 tRFs were up-regulated and 70 tRFs were down-regulated.
Comparision:Differentiated Podocytes VS Undifferentiated Podocytes
Mechanism:N/A