Entry Detail


General Information

Database ID:TRD00277
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tiRNA-Lys-TTT-002
tsRNA Type:5'-tiRNA
Amino acid and Anticodon:LysTTT
Sequence:GCCCGGATAGCTCAGTCGGTAGAGCATCAGACTT
Related Target:N/A
Predicted Target:EBI3//URM1//SEC24C//ARHGEF19//CD3D//TNFRSF11A//ALDOC//MMP21//NDUFA8//PFKP
External Links:
MINTbase ID:tRF-34-PS5P4PW3FJHPEQ
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Lys-TTT-5-1
Anticodon:LysTTT
tRNA_number:trna5
Chromosome:11
Strand:+
Coordinate:Start Site(bp): 59323902        End Site(bp): 59323935

[2] gtRNAdb_ID:tRNA-Lys-TTT-3-1
Anticodon:LysTTT
tRNA_number:trna54
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 204475655        End Site(bp): 204475688

[3] gtRNAdb_ID:tRNA-Lys-TTT-3-2
Anticodon:LysTTT
tRNA_number:trna62
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 204476197        End Site(bp): 204476230

[4] gtRNAdb_ID:tRNA-Lys-TTT-3-4
Anticodon:LysTTT
tRNA_number:trna14
Chromosome:11
Strand:-
Coordinate:Start Site(bp): 59327847        End Site(bp): 59327880

[5] gtRNAdb_ID:tRNA-Lys-TTT-3-5
Anticodon:LysTTT
tRNA_number:trna2
Chromosome:17
Strand:+
Coordinate:Start Site(bp): 8022473        End Site(bp): 8022506

[6] gtRNAdb_ID:tRNA-Lys-TTT-3-3
Anticodon:LysTTT
tRNA_number:trna76
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 28918806        End Site(bp): 28918839



tsRNA Association Statistics

Total Associated Disease Number:11
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D017719N/A
Disease Name:Diabetic FootN/A
Category:MeSHDisease Ontology
Type:Cardiovascular Diseases//Skin and Connective Tissue Diseases//Endocrine System DiseasesN/A
Define:Common foot problems in persons with DIABETES MELLITUS, caused by any combination of factors such as DIABETIC NEUROPATHIES; PERIPHERAL VASCULAR DISEASES; and INFECTION. With the loss of sensation and poor circulation, injuries and infections often lead to severe foot ulceration, GANGRENE and AMPUTATION, SURGICAL.N/A
Alias:Diabetic Feet//Foot Ulcer, DiabeticN/A



Disease Association Statistics

Total Associated tsRNA Number:277
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing//Data Mining



Reference

[1] PubMed ID:34657473
Disease Name:Diabetic Foot
Tissue:Skin
Dysfunction Pattern:Up-Regulation
Validated Method:High-throughput sequencing//Data Mining
Description:In addition, 244 tsRNAs were confirmed to be dysregulated in DFU tissues: 178 tsRNAs were upregulated, whereas 66 tsRNAs were downregulated (DFU vs normal; FC >1.5 and p < 0.05; Figure 2D & Supplementary data 30).
Comparision:DFU VS Normal
Mechanism:N/A