Entry Detail


General Information

Database ID:TRD00253
Confidence:High
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tiRNA-Lys-CTT-002
tsRNA Type:5'-tiRNA
Amino acid and Anticodon:LysCTT
Sequence:GCCCGGCTAGCTCAGTCGGTAGAGCATGAGACTC
Related Target:N/A
Predicted Target:EBI3//NFKBID//CHTF18//JPH1//TNFRSF11A//PES1//MGAT1//POM121C//ALG14//STX18
External Links:
MINTbase ID:tRF-34-PSQP4PW3FJI0E5
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Lys-CTT-2-1
Anticodon:LysCTT
tRNA_number:trna119
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 145395561        End Site(bp): 145395594

[2] gtRNAdb_ID:tRNA-Lys-CTT-2-5
Anticodon:LysCTT
tRNA_number:trna7
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 3225692        End Site(bp): 3225725

[3] gtRNAdb_ID:tRNA-Lys-CTT-2-3
Anticodon:LysCTT
tRNA_number:trna11
Chromosome:5
Strand:-
Coordinate:Start Site(bp): 180649018        End Site(bp): 180649051

[4] gtRNAdb_ID:tRNA-Lys-CTT-2-2
Anticodon:LysCTT
tRNA_number:trna9
Chromosome:5
Strand:+
Coordinate:Start Site(bp): 180634755        End Site(bp): 180634788

[5] gtRNAdb_ID:tRNA-Lys-CTT-2-4
Anticodon:LysCTT
tRNA_number:trna13
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 26556774        End Site(bp): 26556807



tsRNA Association Statistics

Total Associated Disease Number:17
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D000077192DOID:3910
Disease Name:Adenocarcinoma of Lunglung adenocarcinoma
Category:MeSHDisease Ontology
Type:Neoplasmsdisease of anatomical entity//disease of cellular proliferation
Define:A carcinoma originating in the lung and the most common lung cancer type in never-smokers. Malignant cells exhibit distinct features such as glandular epithelial, or tubular morphology. Mutations in KRAS, EGFR, BRAF, and ERBB2 genes are associated with this cancer.A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.
Alias:Lung Adenocarcinomaadenocarcinoma of lung//bronchogenic lung adenocarcinoma//nonsmall cell adenocarcinoma



Disease Association Statistics

Total Associated tsRNA Number:203
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:RT-PCR
Weak Evidence:Data Mining



Reference

[1] PubMed ID:33986867
Disease Name:Adenocarcinoma of Lung
Tissue:N/A
Dysfunction Pattern:Up-Regulation
Validated Method:RT-PCR//Data Mining
Description:Reverse transcription-quantitative PCR verification revealed that the expression levels of tiRNA-Lys-CTT-002,tRF-Val-CAC-010 and tRF-Val-CAC-011 were significantly upregulated,while those of tRF-Ser-TGA-005 were downregulated in lung adenocarcinoma tissues.
Comparision:N/A
Mechanism:N/A