Entry Detail



General Information

Database ID:TRD00211
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tiRNA-His-GTG-001
tsRNA Type:5'-tiRNA
Amino acid and Anticodon:HisGTG
Sequence:GCCGTGATCGTATAGTGGTTAGTACTCTGCGTTG
Related Target:N/A
Predicted Target:SHF//EVPLL//AC010422.3//MAN2B1//ZNF497//MFGE8//SHANK2//ARHGAP25//DDB1//SUSD5
External Links:
MINTbase ID:tRF-34-R9J89O9NF5W8E5
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-His-GTG-1-4
Anticodon:HisGTG
tRNA_number:trna111
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 147774883        End Site(bp): 147774916

[2] gtRNAdb_ID:tRNA-His-GTG-1-1
Anticodon:HisGTG
tRNA_number:trna118
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 145396919        End Site(bp): 145396952

[3] gtRNAdb_ID:tRNA-His-GTG-1-2
Anticodon:HisGTG
tRNA_number:trna16
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 146544773        End Site(bp): 146544806

[4] gtRNAdb_ID:tRNA-His-GTG-1-3
Anticodon:HisGTG
tRNA_number:trna21
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 147753471        End Site(bp): 147753504

[5] gtRNAdb_ID:tRNA-His-GTG-1-9
Anticodon:HisGTG
tRNA_number:trna1
Chromosome:15
Strand:+
Coordinate:Start Site(bp): 45493349        End Site(bp): 45493382

[6] gtRNAdb_ID:tRNA-His-GTG-1-8
Anticodon:HisGTG
tRNA_number:trna8
Chromosome:15
Strand:-
Coordinate:Start Site(bp): 45492649        End Site(bp): 45492682

[7] gtRNAdb_ID:tRNA-His-GTG-1-7
Anticodon:HisGTG
tRNA_number:trna9
Chromosome:15
Strand:-
Coordinate:Start Site(bp): 45490842        End Site(bp): 45490875

[8] gtRNAdb_ID:tRNA-His-GTG-1-5
Anticodon:HisGTG
tRNA_number:trna33
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 27125906        End Site(bp): 27125939

[9] gtRNAdb_ID:tRNA-His-GTG-1-6
Anticodon:HisGTG
tRNA_number:trna7
Chromosome:9
Strand:-
Coordinate:Start Site(bp): 14433976        End Site(bp): 14434009



tsRNA Association Statistics

Total Associated Disease Number:28
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D010051DOID:2394
Disease Name:Ovarian Neoplasmsovarian cancer
Category:MeSHDisease Ontology
Type:Neoplasms//Urogenital Diseases//Endocrine System Diseasesdisease of anatomical entity//disease of cellular proliferation
Define:Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS. A female reproductive organ cancer that is located_in the ovary.
Alias:Cancer of Ovary//Cancer of the Ovary//Neoplasms, Ovarian//Ovarian Cancer//Ovary Cancer//Ovary Neoplasmsmalignant Ovarian tumor//malignant tumour of ovary//ovarian neoplasm//ovary neoplasm//primary ovarian cancer//tumor of the Ovary



Disease Association Statistics

Total Associated tsRNA Number:74
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:33860037
Disease Name:Ovarian Neoplasms
Tissue:Ovarian
Dysfunction Pattern:Up-Regulation
Validated Method:High-throughput sequencing
Description:There are a total of 20 significantly upregulated and 15 significantly downregulated tRFs and tiRNAs between the cancer group and the paracarcinoma group.
Comparision:Cancer VS Normal
Mechanism:The upregulated tRFs and tiRNAs are mucin-type O-glycan biosynthesis, glycosphingolipid biosynthesis, the glucagon signaling pathway, the AMPK signaling pathway, maturity-onset diabetes of the young, glycosphingolipid biosynthesis, the insulin signaling pathway, insulin resistance, leukocyte transendothelial migration, starch, and sucrose metabolism.