Entry Detail


General Information

Database ID:TRD00120
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tiRNA-Glu-TTC-003
tsRNA Type:5'-tiRNA
Amino acid and Anticodon:GluTTC
Sequence:TCCCTGGTGGTCTAGTGGCTAGGATTCGGCGCTT
Related Target:N/A
Predicted Target:PAQR4//TMEM69//RFTN1//BAHCC1//DDX60//TFCP2L1//PHETA1//CHRNB4//SLC25A6//EME2
External Links:
MINTbase ID:tRF-34-87R8WP9I1EWJIQ
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Glu-TTC-8-1
Anticodon:GluTTC
tRNA_number:trna94
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 149664394        End Site(bp): 149664427

[2] gtRNAdb_ID:tRNA-Glu-TTC-4-1
Anticodon:GluTTC
tRNA_number:trna134
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 16861812        End Site(bp): 16861845

[3] gtRNAdb_ID:tRNA-Glu-TTC-4-2
Anticodon:GluTTC
tRNA_number:trna84
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 161391921        End Site(bp): 161391954

[4] gtRNAdb_ID:tRNA-Glu-TTC-3-1
Anticodon:GluTTC
tRNA_number:trna5
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 17199078        End Site(bp): 17199111



tsRNA Association Statistics

Total Associated Disease Number:16
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D017719N/A
Disease Name:Diabetic FootN/A
Category:MeSHDisease Ontology
Type:Cardiovascular Diseases//Skin and Connective Tissue Diseases//Endocrine System DiseasesN/A
Define:Common foot problems in persons with DIABETES MELLITUS, caused by any combination of factors such as DIABETIC NEUROPATHIES; PERIPHERAL VASCULAR DISEASES; and INFECTION. With the loss of sensation and poor circulation, injuries and infections often lead to severe foot ulceration, GANGRENE and AMPUTATION, SURGICAL.N/A
Alias:Diabetic Feet//Foot Ulcer, DiabeticN/A



Disease Association Statistics

Total Associated tsRNA Number:277
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing//Data Mining



Reference

[1] PubMed ID:34657473
Disease Name:Diabetic Foot
Tissue:Skin
Dysfunction Pattern:Up-Regulation
Validated Method:High-throughput sequencing//Data Mining
Description:In addition, 244 tsRNAs were confirmed to be dysregulated in DFU tissues: 178 tsRNAs were upregulated, whereas 66 tsRNAs were downregulated (DFU vs normal; FC >1.5 and p < 0.05; Figure 2D & Supplementary data 98).
Comparision:DFU VS Normal
Mechanism:N/A