Entry Detail



General Information

Database ID:TRD00110
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:AS-tDR-001271
tsRNA Type:5'-tiRNA
Amino acid and Anticodon:GluTTC
Sequence:TCCCATATGGTCTAGCGGTTAGGATTCCTGGTT
Related Target:N/A
Predicted Target:SGMS2//MOB3C//PPP1R26//CLEC18A//CLEC18C//CLEC18B//FRK//COL4A3//CCDC24//PAQR4
External Links:
MINTbase ID:tRF-33-86V8WPMN1E8Y0E
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Glu-TTC-1-2
Anticodon:GluTTC
tRNA_number:trna5
Chromosome:13
Strand:-
Coordinate:Start Site(bp): 41634913        End Site(bp): 41634945

[2] gtRNAdb_ID:tRNA-Glu-TTC-1-1
Anticodon:GluTTC
tRNA_number:trna20
Chromosome:2
Strand:-
Coordinate:Start Site(bp): 131094740        End Site(bp): 131094772



tsRNA Association Statistics

Total Associated Disease Number:2
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D010190DOID:1793
Disease Name:Pancreatic Neoplasmspancreatic cancer
Category:MeSHDisease Ontology
Type:Neoplasms//Digestive System Diseases//Endocrine System Diseasesdisease of anatomical entity//disease of cellular proliferation
Define:Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).An endocrine gland cancer located_in the pancreas.
Alias:Cancer of Pancreas//Cancer of the Pancreas//Neoplasms, Pancreatic//Pancreas Cancer//Pancreas Neoplasms//Pancreatic CancerCa body of pancreas//Ca head of pancreas//Ca tail of pancreas//malignant neoplasm of body of pancreas//malignant neoplasm of head of pancreas//malignant neoplasm of tail of pancreas pancreas neoplasm [EXACT] pancreatic neoplasm [EXACT] pancreatic tumor [EXACT]



Disease Association Statistics

Total Associated tsRNA Number:112
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:31452788
Disease Name:Pancreatic Neoplasms
Tissue:N/A
Dysfunction Pattern:Up-Regulation
Validated Method:High-throughput sequencing
Description:A total of 48 DE-tRFs and tiRNAs were screened from the pancreatic cancer samples and adjacent normal tissue samples, including 46 upregulated tRFs and tiRNAs and 2 downregulated tRFs and tiRNAs (Table III).
Comparision:Cancer VS Adjacent Normal Tissue
Mechanism:N/A