Entry Detail


General Information

Database ID:TRD00099
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tiRNA-Glu-CTC-001
tsRNA Type:5'-tiRNA
Amino acid and Anticodon:GluCTC
Sequence:TCCCTGGTGGTCTAGTGGTTAGGATTCGGCGCTC
Related Target:N/A
Predicted Target:TFCP2L1//PAQR4//EME2//TMEM69//RFTN1//TMEM92//CCDC159//PFKFB3//SLC25A48//TPCN2
External Links:
MINTbase ID:tRF-34-87R8WP9N1EWJI5
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Glu-CTC-2-1
Anticodon:GluCTC
tRNA_number:trna59
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 249168447        End Site(bp): 249168480

[2] gtRNAdb_ID:tRNA-Glu-CTC-1-1
Anticodon:GluCTC
tRNA_number:trna116
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 145399271        End Site(bp): 145399304

[3] gtRNAdb_ID:tRNA-Glu-CTC-1-5
Anticodon:GluCTC
tRNA_number:trna71
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 161439227        End Site(bp): 161439260

[4] gtRNAdb_ID:tRNA-Glu-CTC-1-4
Anticodon:GluCTC
tRNA_number:trna74
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 161431847        End Site(bp): 161431880

[5] gtRNAdb_ID:tRNA-Glu-CTC-1-3
Anticodon:GluCTC
tRNA_number:trna77
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 161424436        End Site(bp): 161424469

[6] gtRNAdb_ID:tRNA-Glu-CTC-1-2
Anticodon:GluCTC
tRNA_number:trna80
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 161417056        End Site(bp): 161417089

[7] gtRNAdb_ID:tRNA-Glu-CTC-1-6
Anticodon:GluCTC
tRNA_number:trna77
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 28949976        End Site(bp): 28950009

[8] gtRNAdb_ID:tRNA-Glu-CTC-1-7
Anticodon:GluCTC
tRNA_number:trna87
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 126101431        End Site(bp): 126101464



tsRNA Association Statistics

Total Associated Disease Number:28
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D006333N/A
Disease Name:Heart FailureN/A
Category:MeSHDisease Ontology
Type:Cardiovascular DiseasesN/A
Define:A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.N/A
Alias:Cardiac Failure//Congestive Heart Failure//Heart Decompensation//Heart Failure, Congestive//Heart Failure, Left-Sided//Heart Failure, Right-Sided//Left-Sided Heart Failure//Myocardial Failure//Right-Sided Heart FailureN/A



Disease Association Statistics

Total Associated tsRNA Number:81
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing//Data Mining



Reference

[1] PubMed ID:37839439
Disease Name:Heart Failure
Tissue:Epicardial Adipose Tissue
Dysfunction Pattern:Up-Regulation
Validated Method:High-throughput sequencing//Data Mining
Description:Of those, a total of 24 tsRNAs were significantly differentially expressed between HF and controls: 17 were upregulated and 7 were downregulated (fold change >1.5, p < 0.05).
Comparision:HF VS Control
Mechanism:N/A